By Sandeep Ravindran Posted September 4, 2009
Scientists have developed a gel that helps brains recover from traumatic injuries. It has the potential to treat head injuries suffered in combat, car accidents, falls, or gunshot wounds. Developed by Dr. Ning Zhang at Clemson University in South Carolina, the gel is injected in liquid form at the site of injury and stimulates the growth of stem cells there.
Brain injuries are particularly hard to repair, since injured tissues swell up and can cause additional damage to the cells. So far, treatments have tried to limit this secondary damage by lowering the temperature or relieving the pressure at the site of injury. However, these techniques are often not very effective.
More recently, scientists have considered transplanting donor brain cells into the wound to repair damaged tissue. This method has so far had limited results when treating brain injuries. The donor cells often fail to grow or stimulate repair at the injury site, possibly because of the inflammation and scarring present there. The injury site also typically has very limited blood supply and connective tissue, which might prevent donor cells from getting the nutrients they require.
Dr. Zhang's gel, however, can be loaded with different chemicals to stimulate various biological processes at the site of injury. In previous research done on rats, she was able to use the gel to help re-establish full blood supply at the site of brain injury. This could help create a better environment for donor cells.
In a follow-up study, Dr. Zhang loaded the gel with immature stem cells, as well as the chemicals they needed to develop into full-fledged adult brain cells. When rats with severe brain injuries were treated with this mixture for eight weeks, they showed signs of significant recovery.
The new gel could treat patients at varying stages following injury, and is expected to be ready for testing in humans in about three years.
Ravindran, Sandeep. "A Squirt of Stem Cell Gel Heals Brain Injuries."
Popular Science. N.p., 4 Sept. 2009. Web. 28 Sept. 2015.
From <http://www.easybib.com/cite/view>
This Article discusses the prospect of a new brain injury treatment. This article was written in 2009, hoping for this treatment to be applicable to human patients by 2012, however there are no updated articles confirming the success of that hope. Seeing as how this would be a major development in the medical world, it is strange to me for there not to be a follow up article. This article does not have a huge bias, but is biased in its failure to mention any downsides to this treatment. It is possible that there aren't any downsides but that is very unlikely. This article also fails to mention how the rats they used for their treatment acquired brain injuries as well as how they were given that diagnosis. I think this is an exciting prospect for the medical world, but was sad to see that there were no articles on how the treatment worked on humans.